Behind the Scenes Videos

Key Points:

• New strategies to durably reduce Lp(a) have great promise for loweing risk of MACE.
• Small interfering DNA or RNA particles are being designed to block lipoprotein a particle formation in hepatocytes.
• CRISPR technology may also be capable of knocking out the Lp (a) gene.
• These therapies have the potential to decrease Lp (a) and reduct CV risk over the longterm.

Key Points:

• Elevated Lp (a) is common and strongly associated with atherosclerotic vascular disease and aortic stenosis.
• Lp (a) levels are largely genetically determined.
• Lp (a) elevation in one family member may indicate that others should be tested.
• People with highly elevated Lp (a) benefit from intensified measures to reduce CV risk (i.e. lifestyle modification, statin, and aspirin therapy).

To learn more about lipoprotein (a) testing and implications, check out the 5-Pearls episode at our website! You can also check out more videos like this one by subscribing to our YouTube Channel. Thanks for watching!